General Cell Based Assays
Eurofins Discoverx cAMP Hunter eXpress ADRB1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0113E2CP2L)
The cAMP Hunter ADRB1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB1, a naturally Gs coupled GPCR. Upon activation of ADRB1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress ADRB1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0113E2CP2M)
The cAMP Hunter ADRB1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. isoproterenol) based activation of ADRB1 GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type ADRB1, a naturally Gs coupled GPCR. Upon activation of ADRB1, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress GLP2R CHO-K1 GPCR Assay, 2-Plate Kit. (95-0112E2CP2M)
The cAMP Hunter GLP2R eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. GLP-2) based activation of GLP2R GPCR activity via detection of increasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type GLP2R, a naturally Gs coupled GPCR. Upon activation of GLP2R, the increase in levels of intracellular cAMP leads to an increased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress NPFFR1 CHO-K1 GPCR Assay, 2-Plate Kit. (95-0097E2CP2M)
The cAMP Hunter NPFFR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuropeptide FF, RFRP-3) based activation of NPFFR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type NPFFR1, a naturally Gi/Go coupled GPCR. Upon activation of NPFFR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx cAMP Hunter eXpress NPFFR1 CHO-K1 GPCR Assay, 10-Plate Kit. (95-0097E2CP2L)
The cAMP Hunter NPFFR1 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. neuropeptide FF, RFRP-3) based activation of NPFFR1 GPCR activity via detection of decreasing levels of intracellular cAMP. This product uses EFC technology. The cells overexpress wild type NPFFR1, a naturally Gi/Go coupled GPCR. Upon activation of NPFFR1, the decrease in levels of intracellular cAMP leads to a decreased signal from EFC when the cAMP detection kit is applied. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Meso Scale Discovery VPLEX GLP1 Total Kit 25 PL
The Meso Scale Discovery V-PLEX GLP-1 Total Kit is an electrochemiluminescent immunoassay for the quantitative measurement of total glucagon-like peptide-1 (GLP-1) in human serum plasma and cell culture supernatants The assay utilizes MSD s proprietary SULFO-TAG labels and multi-array technology to provide sensitive and reproducible results with a broad dynamic range and rapid protocol This kit includes a 96-well plate coated with capture antibody detection antibody conjugated to ruthenium label calibrators and reagents required to perform the assay The lower limit of detection is 1 5 pg/mL with an upper limit of 10 000 pg/mL
Meso Scale Discovery U-PLEX Human MCP-2 ASY 25 PL
The Meso Scale Discovery U-PLEX Human MCP-2 Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of the human chemokine MCP-2 It utilizes MSD s proprietary electrochemiluminescent detection technology and is provided in a convenient all-in-one kit containing plates coated with capture antibodies detection antibodies calibrators and buffers The assay has high sensitivity and wide dynamic range requires low sample volume and provides rapid results It is intended for research use only to monitor MCP-2 levels in cell culture supernatants serum plasma and other biological samples
Meso Scale Discovery U-PLEX Human Perforin ASY
The Meso Scale Discovery U-PLEX Human Perforin Assay is a multiplex immunoassay that measures the levels of perforin in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements This assay allows for the simultaneous measurement of perforin along with other biomarkers in the same sample to understand immune response It requires 50 L of sample and can perform up to 80 tests per kit The kit includes a 96-well plate coated with capture antibodies detection antibodies read buffer wash buffer calibrator and controls
Meso Scale Discovery R-PLEX Human ADAM17 ASY
The R-PLEX Human ADAM17 Assay Kit from Meso Scale Discovery is a multiplex immunoassay that measures active ADAM17 in human serum plasma and cell culture supernatants The assay utilizes MSD s electrochemiluminescent detection technology and provides high sensitivity a broad dynamic range and requires a low sample volume The kit includes a 96-well plate coated with capture antibody a detection antibody and calibrator The assay can detect ADAM17 levels between 1 5-1000 pg/mL and each kit provides sufficient reagents for 1 x 96-well plate This product enables the accurate quantitation of ADAM17 which plays a key role in regulating EGFR signaling
Meso Scale Discovery Rat NT-proANP Kit
The Meso Scale Discovery Rat NT-proANP Kit is an electrochemiluminescent immunoassay for the quantitative determination of NT-proANP in rat serum plasma and cell culture supernatants The assay uses MSD s proprietary SULFO-TAG labels and MULTI-ARRAY technology with triplexed immunoassays to provide sensitive accurate and rapid quantification of NT-proANP from a small sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies labeled with MSD SULFO-TAG calibrators and sample diluent The kit has a typical sensitivity of 0 3 pg/mL and an assay time of 2 5 hours
Meso Scale Discovery R-PLEX Human IL-36 ASY
The Meso Scale Discovery R-PLEX Human IL-36gamma Assay is a multiplex immunoassay panel that allows simultaneous quantitative measurement of IL-36gamma in human serum plasma and cell culture supernatants It utilizes electrochemiluminescence (ECL) detection technology and provides high sensitivity up to 5-logs of dynamic range and low sample volume requirements This assay kit includes a plate coated with capture antibodies detection antibodies labeled with an ECL compound and calibrator and control solutions for generating standard curves and evaluating run validity It allows sensitive reproducible quantification of IL-36gamma levels from human samples
Meso Scale Discovery R-PLEX Human IL-19 ASY
The R-PLEX Human IL-19 Assay Kit from Meso Scale Discovery is a multiplex immunoassay for measuring IL-19 in human serum plasma and cell culture supernatants It uses MSD s electrochemiluminescent detection technology offering high sensitivity a 5-log dynamic range and low sample volume needs The kit includes a 96-well plate with capture antibodies for IL-19 detection antibodies calibrators and diluents The assay takes about 3 5 hours and detects IL-19 as low as 17 pg/mL making it a sensitive and efficient tool for quantifying IL-19 in biological samples
Revvity Health Sciences Inc AlphaLISA SureFire Ultra Multiplex Human & Mouse Phospho-SMAD2 (Ser465/467 & Total) Detection Kit, 10,000 Assay Points
AlphaLISA SureFire Ultra Multiplex Human & Mouse Phospho-SMAD2 (Ser465/467 & Total) Detection Kit, 10,000 Assay Points
Meso Scale Discovery U-PLEX Mouse IL-16 ASY
The Meso Scale Discovery U-PLEX Mouse IL-16 Assay is a multiplex immunoassay kit that enables simultaneous quantification of mouse interleukin 16 (IL-16) in serum plasma and cell culture supernatants This electrochemiluminescent assay utilizes MSD s proprietary SECTOR Imager and provides high sensitivity a wide dynamic range and requires low sample volume The kit includes a 96-well plate pre-coated with capture antibodies detection antibodies calibrators and controls for generating a standard curve and measuring IL-16 levels accurately This assay allows efficient reproducible analysis of IL-16 an immunomodulatory cytokine involved in inflammatory and autoimmune responses
Meso Scale Discovery R-PLEX Rat IL-13 ASY
The R-PLEX Rat IL-13 Assay from Meso Scale Diagnostics is a multiplex immunoassay that measures rat interleukin 13 (IL-13) in serum plasma and cell culture supernatants This assay uses electrochemiluminescence (ECL) detection technology and provides high sensitivity broad dynamic range and requires low sample volume The assay has high specificity and shows minimal cross-reactivity The kit includes a 96-well plate coated with capture antibody detection antibody read buffer wash buffer blocker reagents and calibrator The assay takes 3 5 hours to complete and has a sensitivity of 0 3 pg/mL